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Product Overview
| Product Name | TREM2 Polyclonal Antibody |
|---|---|
| Catalog Number | GRP489 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | FC, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from human TREM2 (public_immunogen_range: 20-70/230) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Application Notes
| Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400 |
|---|
Validation Images
Formalin-fixed and paraffin embedded human gastritis labeled with Rabbit Anti TREM2 Polyclonal Antibody, Unconjugated (bs-2723R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Lane 1: MCF-7 cell lysates; Lane 2: Raw264.7 cell lysates probed with TREM2 Polyclonal Antibody, Unconjugated (bs-2723R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
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