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Product Overview
| Product Name | Connexin 43 Polyclonal Antibody |
|---|---|
| Catalog Number | GRP285 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat, Dog |
| Conjugation | Unconjugated |
| Tested applications | FC, ICC, IF, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from human Connexin-43 (public_immunogen_range: 232-282/282) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
Application Notes
| Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200 |
|---|
Validation Images
WB of GRP285
IHC-P of GRP285
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