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WWOX Polyclonal Antibody

Catalog Number: GRP271

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Datasheet
Product Overview
Product Name WWOX Polyclonal Antibody
Catalog Number GRP271
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human WWOX (public_immunogen_range: 1-50/414)
Alternative Names (click to expand) FOR; WOX1; EIEE28; FRA16D; SCAR12; HHCMA56; PRO0128; SDR41C1; D16S432E; WW domain-containing oxidoreductase; Fragile site FRA16D oxidoreductase; Short chain dehydrogenase/reductase family 41C member 1; WWOX
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID Q9NZC7
Entrez 51741
Product Description

Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400
Validation Images
WB of GRP271
WB of GRP271
IHC-P of GRP271
IHC-P of GRP271
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