Availability
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Product Overview
| Product Name | VEGF Polyclonal Antibody |
|---|---|
| Catalog Number | GRP226 |
| Species/Host | Rabbit |
| Reactivity | Human |
| Conjugation | Unconjugated |
| Tested applications | FC, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from human VEGF (public_immunogen_range: 27-77/232) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
Application Notes
| Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP226
IHC-P of GRP226
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