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THDOC - Tetrahydrodeoxycorticosterone
Catalog Number: GRP12213
Product Overview
| Product Name | THDOC - Tetrahydrodeoxycorticosterone |
|---|---|
| Catalog Number | GRP12213 |
| Species/Host | Chicken |
| Tested applications | RIA |
| Immunogen | BSA-coupled THDOC |
Product Properties
| Form/Appearance | Liquid in PBS pH 8.0, 0.02% sodium azide |
|---|---|
| Storage | Store at 4°C or at -20°C for long-term storage; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Total IgY |
Application Notes
| Dilution Range | 1 : 1000 (RIA) |
|---|---|
| Application Notes | Background: TetraHydroDesOxyCorticosterone (THDOC) is a stress related neuroactive steroid. THDOC is a metabolite of desoxycoritcosterone (DOC) and progesterone and DOC is a steroid in the synthesis pathway to aldosterone. THDOC is produced by the adrenal in parallel with cortisol at stress and is regulated by ACTH. THDOC is a potent positive modulator of the GABA A receptor. THDOC passes the blood-brain barrier and can be found in the brain after stress in nanomolar concentrations. |
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