Availability
- Request Lead Time
- In stock and ready for quick dispatch
- Usually dispatched within 5-10 working days
Product Overview
| Product Name | SOX2 Polyclonal Antibody |
|---|---|
| Catalog Number | GRP257 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | FC, ICC, IF, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from mouse Transcription factor SOX-2 (public_immunogen_range: 230-280/319) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Application Notes
| Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200 |
|---|
Validation Images
WB of GRP257
IHC-P of GRP257
Reviews
Write Your Own Review
