SHP-2/PTPN11 Polyclonal Antibody

Catalog Number: GRP371

Product Overview

Product Name	SHP-2/PTPN11 Polyclonal Antibody
Catalog Number	GRP371
Species/Host	Rabbit
Reactivity	Human, Mouse, Rat
Conjugation	Unconjugated
Tested applications	IHC-P, WB
Immunogen	KLH conjugated synthetic peptide derived from human PTPN11 (public_immunogen_range: 515-560/597)
Alternative Names	(click to expand) CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; PTPN11; SHPTP2

Product Properties

Form/Appearance	Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration	1ug/ul
Storage	Store at -20°C for 12 months.
Note	For research use only.
Isotype	IgG
Clonality	Polyclonal
Purity	Purified by Protein A.
Uniprot ID	Q06124
Entrez	5781

Product Description

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.

Application Notes

Dilution Range	WB: 1:300-1000, IHC-P: 1:200-400

Validation Images

WB of GRP371

IHC-P of GRP371

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