SARS-CoV-2 trimeric spike protein (D614G)

Catalog Number: GRP10348

Product Overview
Product Name SARS-CoV-2 trimeric spike protein (D614G)
Catalog Number GRP10348
Product Properties
Concentration 1 mg/ml
Storage -20
Note For research use only.
Product Description


Mopdification C-terminal transmembrane region replaced with a trimerization domain and a polyhistidine tag. Two stabilizing proline mutations and scrambled S1/S2 furin cleavage site (see reference). D614G mutation.
Isolate (Seq ID) Wuhan-Hu-1 (GenBank: MN908947), D614G mutation
Expression System CHOExpressTM cells
Purity > 90 % as determined by SDS-PAGE
Conjugate  His
N-terminus VNLT
Molecular Weight The recombinant SARS-CoV-2 trimeric spike protein consists of 3576 amino acids with a predicted molecular mass of ~400 kDa
Endotoxin <1.0 EU per μg protein as determined by the LAL method
Format Liquid
Concentration 1.0 mg/ml
Buffer 0.01M PBS, pH 7.4
Preservative  None
Storage Store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Ship  Shipped on dry ice


Wrapp D. et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 367, 1260–1263 (2020)

Write Your Own Review
You're reviewing:SARS-CoV-2 trimeric spike protein (D614G) - GRP10348
Your Rating