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Product Overview
| Product Name | S5a - human 26S proteasome subunit |
|---|---|
| Catalog Number | GRP12177 |
| Species/Host | Rabbit |
| Reactivity | Human |
| Tested applications | WB |
| Immunogen | Recombinant human S5a Proteasome subunit also known as Rpn10 P55036 |
Product Properties
| Form/Appearance | Lyophilized |
|---|---|
| Storage | Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Serum |
| MW | 40 kDa |
| Uniprot ID | P55036 |
Application Notes
| Dilution Range | 1 : 2000 (WB) |
|---|---|
| Application Notes | Background: Proteasome-dependent degradation serves an essential role in the removal of a wide variety of key nuclear and cytosolic proteins. Substrates are targeted for proteolysis by the ubiquitin pathway before being degraded by the 26 S proteasome. The subunit of the proteasome, S5a, was identified to bind to polyubiquitin in vitro and thus proposed to act as a substrate recognition component. Alternative names: 26S proteasome non-ATPase regulatory subunit 4, Rpn10, multiubiquitin chain-binding protein, antisecretory factor 1, ASF, AF Reconstitution: For reconstitution add 100 µl of sterile water. |
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