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Product Overview
| Product Name | RPS6KB1(Thr 412) Polyclonal Antibody |
|---|---|
| Catalog Number | GRP566 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human RPS6KB1 around the phosphorylation site of Thr412 |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
|---|---|
| Concentration | 1ug/ul |
| Storage | Store at -20°C for 12 months. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Purity | Purified by Protein A. |
| Entrez | 6198 |
Product Description
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP566
IHC-P of GRP566
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