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Product Overview
| Product Name | RAR Beta Polyclonal Antibody |
|---|---|
| Catalog Number | GRP254 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | ICC, IF, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from mouse RAR Beta (public_immunogen_range: 148-182/455) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400, IF: 1:50-200 |
|---|
Validation Images
WB of GRP254
IHC-P of GRP254
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