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Product Overview
Product Name | Rad51 Polyclonal Antibody |
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Catalog Number | GRP622 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human Rad51 (public_immunogen_range: 115-145/339) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Application Notes
Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
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