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Product Overview
        
                           
                                                
                                                        
                                    
    
        | Product Name | Rad51 Polyclonal Antibody | 
|---|---|
| Catalog Number | GRP622 | 
| Species/Host | Rabbit | 
| Reactivity | Human, Mouse, Rat | 
| Conjugation | Unconjugated | 
| Tested applications | IHC-P, WB | 
| Immunogen | KLH conjugated synthetic peptide derived from human Rad51 (public_immunogen_range: 115-145/339) | 
| Alternative Names | (click to expand) | 
Product Properties
        
    
        Product Description
        
                           
                             
                    
    
        Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Application Notes
        
                           
                                                
                                                        
                                    
    
        
        | Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 | 
|---|
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