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Product Overview
| Product Name | Nrf2 (Ser40) Polyclonal Antibody |
|---|---|
| Catalog Number | GRP448 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IF, IHC-Fr, IHC-P, WB |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40 [DF(p-S)QR] (public_immunogen_range: 15-65/605) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400, IHC-Fr: 1:100-500, IF: 1:50-200 |
|---|
Validation Images
WB of GRP448
IHC-P of GRP448
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