NOX2/gp91phox Polyclonal Antibody

Catalog Number: GRP527

Product Overview

Product Name	NOX2/gp91phox Polyclonal Antibody
Catalog Number	GRP527
Species/Host	Rabbit
Reactivity	Human, Mouse, Rat
Conjugation	Unconjugated
Tested applications	ICC, IF, IHC-P, WB
Immunogen	KLH conjugated synthetic peptide derived from human NOX2/gp91phox (public_immunogen_range: 490-540/570)
Alternative Names	(click to expand) CGD; NOX2; IMD34; AMCBX2; GP91-1; GP91PHOX; p91-PHOX; GP91-PHOX; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; p22 phagocyte B-cytochrome; CYBB

Product Properties

Form/Appearance	Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration	1ug/ul
Storage	Store at -20°C for 12 months.
Note	For research use only.
Isotype	IgG
Clonality	Polyclonal
Purity	Purified by Protein A.
Uniprot ID	P04839
Entrez	1536

Product Description

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Application Notes

Dilution Range	WB: 1:300-1000, IHC-P: 1:200-400, IF: 1:50-200

Validation Images

WB of GRP527

IHC-P of GRP527

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