Availability
- Request Lead Time
- In stock and ready for quick dispatch
- Usually dispatched within 5-10 working days
Product Overview
| Product Name | NFKBIA(Tyr305) Polyclonal Antibody |
|---|---|
| Catalog Number | GRP564 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Tyr305 (public_immunogen_range: 295-310/317) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP564
IHC-P of GRP564
Reviews
Write Your Own Review
