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- Usually dispatched within 5-10 working days
Product Overview
| Product Name | NFKBIA/IKB alpha Polyclonal Antibody |
|---|---|
| Catalog Number | GRP377 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from mouse IKB alpha (public_immunogen_range: 5-34/314) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP377
IHC-P of GRP377
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