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Product Overview
Product Name | N-cadherin Polyclonal Antibody |
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Catalog Number | GRP363 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human N-cadherin (public_immunogen_range: 746-790/906) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).
Application Notes
Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
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