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Product Overview
| Product Name | IL2RA Polyclonal Antibody |
|---|---|
| Catalog Number | GRP270 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from mouse CD25/IL2RA (public_immunogen_range: 258-268/268) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009].
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP270
IHC-P of GRP270
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