IL-6R Beta/CD130/gp130 Antibody

Catalog Number: GRP403

Product Overview

Product Name	IL-6R Beta/CD130/gp130 Antibody
Catalog Number	GRP403
Species/Host	Rabbit
Reactivity	Human, Mouse, Rat
Conjugation	Unconjugated
Tested applications	IHC-P, WB
Immunogen	KLH conjugated synthetic peptide derived from mouse IL6R beta (public_immunogen_range: 685-735/917)
Alternative Names	(click to expand) Interleukin-6 receptor subunit beta; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6R-beta; IL-6RB; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; Oncostatin-M receptor subunit alpha; CD130; Il6st

Product Properties

Form/Appearance	Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration	1ug/ul
Storage	Store at -20°C for 12 months.
Note	For research use only.
Isotype	IgG
Clonality	Polyclonal
Purity	Purified by Protein A.
Uniprot ID	Q00560
Entrez	16195

Product Description

Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development.

Application Notes

Dilution Range	WB: 1:300-1000, IHC-P: 1:200-400

Validation Images

WB of GRP403

IHC-P of GRP403

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