Availability
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- Usually dispatched within 5-10 working days
Product Overview
| Product Name | IL-6 Polyclonal Antibody |
|---|---|
| Catalog Number | GRP307 |
| Species/Host | Rabbit |
| Reactivity | Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from mouse IL-6 (public_immunogen_range: 130-160/211) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP307
IHC-P of GRP307
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