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IKB alpha (Ser36) Polyclonal Antibody

Catalog Number: GRP621

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Datasheet
Product Overview
Product Name IKB alpha (Ser36) Polyclonal Antibody
Catalog Number GRP621
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human phospho-IKB alpha (Ser36) (public_immunogen_range: 20-50/317)
Alternative Names (click to expand) IKB alpha (phospho S36); p-IKB alpha (phospho S36); I kappa B alpha; I-kappa-B-alpha; IkappaBalpha; IkB-alpha; IKBA; IKBA_HUMAN; IKBalpha; MAD 3; MAD3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappa-B inhibitor alpha; NFKBI; NFKBIA; Nuclear factor of kappa light chain gene enhancer in B cells; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha.
Product Properties
Form/Appearance 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration 1ug/ul
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID P25963
Entrez 4792
Product Description

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400
Validation Images
WB of GRP621
WB of GRP621
IHC-P of GRP621
IHC-P of GRP621
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