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Product Overview
| Product Name | HSP70 1A/1B Polyclonal Antibody |
|---|---|
| Catalog Number | GRP225 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from human HSP70 1A/1B |
| Alternative Names | (click to expand) |
Product Properties
Product Description
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP225
IHC-P of GRP225
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