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Product Overview
Product Name | HMGB1 Polyclonal Antibody |
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Catalog Number | GRP286 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | FC, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human HMGB1 (public_immunogen_range: 60-110/215) |
Alternative Names | (click to expand) |
Product Properties
Product Description
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Application Notes
Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400 |
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