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Gametogenetin Polyclonal Antibody

Catalog Number: GRP618

Product Overview
Product Name Gametogenetin Polyclonal Antibody
Catalog Number GRP618
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications IHC-P
Immunogen KLH conjugated synthetic peptide derived from human GGN/Gametogenetin (public_immunogen_range: 2-25/652)
Alternative Names
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Entrez 199720
Product Description

Gametogenetin is a 652 amino acid protein that is primarily expressed in testis and ovary. Interacting with POG (proliferation of germ cells), GGNBP1 and LCRG1, gametogenetin is likely involved in spermatogenesis. Gametogenetin exists as three alternatively spliced isoforms commonly known as gametogenetin protein 1 (GGN1), gametogenetin protein 2 (GGN2) and gametogenetin protein 3 (GGN3), which localize to nuclear membrane, cytoplasm and nucleus/nucleoli, respectively. GGN1 contains two transmembrane domains in its N-terminal half and 2 C-terminal arginine- and lysine-rich nucleolar targeting sequences. GGN1 and GGN3 are likely linked to germ cell development and both GGN1 and GGN2 may be involved in cell trafficking.

Application Notes
Dilution Range IHC-P: 1:200-400
Validation Images
WB of GRP618
IHC-P of GRP618
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