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Product Overview
| Product Name | GAB2 (Ser159) Polyclonal Antibody |
|---|---|
| Catalog Number | GRP506 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Ser159 (public_immunogen_range: 130-170/676) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP506
IHC-P of GRP506
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