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Product Overview
| Product Name | Enbrel - Etanercept |
|---|---|
| Catalog Number | GRP13228 |
| Species/Host | Chicken |
| Reactivity | Human |
| Predicted Reactivity | Human |
| Immunogen | Purified, recombinant human Enbrel® |
Product Properties
| Form/Appearance | Liquid in 0.9% NaCl, 0.1% sodium azide |
|---|---|
| Storage | Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Total IgY |
| MW | 150 kDa (Enbrel) |
Application Notes
| Dilution Range | 1 : 5 000 (ELISA), 1 : 5 000 (WB) |
|---|---|
| Application Notes | Additional Information: The antibody has no reactivity against TNF alfa. Up to date no tests have been done against TNFR1.Total IgY concentration for this antibody is 20 mg/ml The antibody has been used as a detecting antibody in ELISA against Enbrel attached to the surface. It gave a good signal and suggested dilution for this experiment is 1: 1000 – 1 : 5000. Background: Etanercept (Enbrel®), is a recombinant human tumor necrosis factor receptor (TNFRSF1B). Enbrel® consist of the extracellular ligand-binding portion of TNFRSF1B linked to an immunoglobulin Fc chain. It binds to TNF-alpha and blocks its interactions with receptors. |
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