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Product Overview
| Product Name | Diglyceride acyltransferase Antibody |
|---|---|
| Catalog Number | GRP467 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P |
| Immunogen | KLH conjugated synthetic peptide derived from human DGAT1 (public_immunogen_range: 285-330/488) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Application Notes
| Dilution Range | IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP467
IHC-P of GRP467
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