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Cryopyrin Polyclonal Antibody

Catalog Number: GRP597

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Datasheet
Product Overview
Product Name Cryopyrin Polyclonal Antibody
Catalog Number GRP597
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human Cryopyrin (public_immunogen_range: 1-50/1036)
Alternative Names (click to expand) NACHT, LRR and PYD domains-containing protein 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID Q96P20
Entrez 114548
Product Description

May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400
Validation Images
WB of GRP597
WB of GRP597
IHC-P of GRP597
IHC-P of GRP597
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