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Product Overview
Product Name | CDKN1B Polyclonal Antibody |
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Catalog Number | GRP298 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | FC, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from human CDKN1B (public_immunogen_range: 150-198/198) |
Alternative Names | (click to expand) |
Product Properties
Product Description
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Application Notes
Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400 |
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