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Product Overview
Product Name | CD14 Polyclonal Antibody |
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Catalog Number | GRP365 |
Species/Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |
Tested applications | FC, IHC-P, WB |
Immunogen | KLH conjugated synthetic peptide derived from mouse CD14 (public_immunogen_range: 240-270/366) |
Alternative Names | (click to expand) |
Product Properties
Product Description
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).
Application Notes
Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400 |
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