CD11b/c Polyclonal Antibody

Catalog Number: GRP333

Product Overview

Product Name	CD11b/c Polyclonal Antibody
Catalog Number	GRP333
Species/Host	Rabbit
Reactivity	Human, Mouse, Rat
Conjugation	Unconjugated
Tested applications	FC, IHC-P, WB
Immunogen	KLH conjugated synthetic peptide derived from human CD11b (public_immunogen_range: 50-100/1152)
Alternative Names	(click to expand) CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; ITGAM; Integrin alpha-X; ITGAX; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c

Product Properties

Form/Appearance	Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration	1ug/ul
Storage	Store at -20°C for 12 months.
Note	For research use only.
Isotype	IgG
Clonality	Polyclonal
Purity	Purified by Protein A.
Uniprot ID	P11215
Entrez	3684

Product Description

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Application Notes

Dilution Range	WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400

Validation Images

WB of GRP333

IHC-P of GRP333

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