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Product Overview
| Product Name | ExoS - Exoenzyme S |
|---|---|
| Catalog Number | GRP12190 |
| Species/Host | Chicken |
| Reactivity | Bacteria |
| Predicted Reactivity | Pseudomonas aeruginosa |
| Tested applications | WB |
| Immunogen | amino acids 366 to 453 of PA3841 of ADP-rbosylating enzyme - Exoenzyme S overexpressed in a GST fusion. Afterwards cleaved with a help of trombin and separated on a polyacrylamide gel. Gel piece has been used for immunizations. |
Product Properties
| Form/Appearance | Liquid in PBS pH 8.0, 0.02% sodium azide |
|---|---|
| Storage | Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Total IgY |
| MW | 48 kDa |
| Uniprot ID | Q51449 , PA3841 |
Application Notes
| Dilution Range | 1 : 5000 (WB) |
|---|---|
| Application Notes | Background: Exoenzyme S (ExoS) is a toxin directly translocated into eukaryotic cells by the type III secretory process of Pseudomonas aeruginosa. It is a bi-functional toxin and contain an N-terminal Rho GAP domain that disrupts the actin cytoskeleton and interference of phagocytosis. The C-terminal of ExoS contains an ADP-ribosyltransferase domain, which elicits a cytotoxic phenotype in cultured cells. |
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