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MYST4 - histone acetyltransferase KAT6B
Catalog Number: GRP12197
Product Overview
| Product Name | MYST4 - histone acetyltransferase KAT6B |
|---|---|
| Catalog Number | GRP12197 |
| Species/Host | Rabbit |
| Reactivity | Bovine |
| Predicted Reactivity | Black flying fox, Human (isoform 2,3), Mouse (isoform 2,3,4), Vampire bat |
| Tested applications | IP, WB, IHC |
| Immunogen | KLH-conjugated synthetic peptide chosen from a bovine histone acetyltrasferase MYST4 A7E390 |
Product Properties
| Form/Appearance | Lyophilized in PBS pH 7.4 |
|---|---|
| Storage | Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Affinity purified serum |
| MW | 230 kDa |
| Uniprot ID | A7E390 |
Application Notes
| Dilution Range | 1 : 1000 (IHC), 1 :7500 (WB) |
|---|---|
| Application Notes | Additional Information: Blocking used in IHC was done with 5% dry milk. Secondary antibodyused: Fluorescein-conjugated goat anti-rabbit IgG (Molecular Probes) diluted 1:1000. Antibody has been used on extracts from bovine brain, thymus, muscle, lung, heart, liver, kidney and spleen Background: MYST4 (KAT6B), EC=2.3.1.48, is a transcriptional coactivator with histone acetyltransferase activity. This protein is essential for normal mouse embryo development. Mouse mutants for MYST4 show craniofacial abnormalities, retards in post-natal development, defaults in the nervous system and neurogenique problems. Abnormal chromosomic rearengements of MYST4 with the CBP gene is involved in acute myeloid leukaemia (AML)-M4. Furthermore, in the ovary and the testis of mammals, MYST4 is mainly localized in specialized cells involved in male and female gametogenesis. Alternative names: Histone acetyltransferase MOZ2, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4, Monocytic leukemia zinc finger protein-related factor. Reconstitution: For reconstitution add 125 µl of sterile water. |
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