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Product Overview
| Product Name | NADPH oxidase 4 Polyclonal Antibody |
|---|---|
| Catalog Number | GRP348 |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat, Dog |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from mouse Nox-4 (public_immunogen_range: 84-105/578) |
| Alternative Names | (click to expand) |
Product Properties
Product Description
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Application Notes
| Dilution Range | WB: 1:300-1000, IHC-P: 1:200-400 |
|---|
Validation Images
WB of GRP348
IHC-P of GRP348
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