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Product Overview
| Product Name | Anti-Hu CD51/CD61 Purified |
|---|---|
| Catalog Number | GRP13265 |
| Reactivity | Human, Chicken |
| Tested applications | FC, IHC-Fr, IP |
| Immunogen | A cell suspension containing osteoclasts from osteoclastomas |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Purified |
|---|---|
| Concentration | 1 mg/ml |
| Preservatives | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Note | For research use only. |
| Isotype | Mouse IgG1 |
| Clone ID | 23C6 |
Product Description
CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.
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