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Product Overview
| Product Name | Anti-HLA-E Purified |
|---|---|
| Catalog Number | GRP10619 |
| Reactivity | Human, Primate |
| Tested applications | FC, IHC-P, IP |
| Immunogen | Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide. |
| Alternative Names | (click to expand) |
Product Properties
| Concentration | 1 mg/ml |
|---|---|
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Note | For research use only. |
| Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Clone ID | MEM-E/06 |
| Uniprot ID | P13747 |
| NCBI | 3133 |
Product Description
The antibody MEM-E/06 recognizes an extracellular epitope on native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
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