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Product Overview
| Product Name | Anti-Ms LPAM-1 Purified Azide Free |
|---|---|
| Catalog Number | GRP13253 |
| Reactivity | Mouse |
| Tested applications | FA, IHC-Fr, IP |
| Immunogen | TK1 cells |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Purified Azide Free |
|---|---|
| Concentration | 1 mg/ml |
| Preservatives | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Note | For research use only. |
| Isotype | Rat IgG2a kappa |
| Clone ID | DATK32 |
Product Description
Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Lymphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.
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