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beta 2 Adrenergic Receptor antibody [C2C3], C-term

Catalog Number: GRP92

Product Overview
Product Name beta 2 Adrenergic Receptor antibody [C2C3], C-term
Catalog Number GRP92
Species/Host Rabbit
Reactivity Human, Rat
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human beta 2 Adrenergic Receptor. The exact sequence is proprietary.
Alternative Names
Product Properties
Form/Appearance Liquid: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration 1 mg/ml
Storage Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by antigen-affinity chromatography.
Uniprot ID P07550
Entrez 154
Product Description

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq]

Application Notes
Dilution Range WB: 1:500-1:3000,IHC-P: 1:100-1:1000
Validation Images
Sample (30 μg of whole cell lysate) A: PC-12 10% SDS PAGE GRP544 diluted at 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
beta 2 Adrenergic Receptor antibody [C2C3], C-term detects beta 2 Adrenergic Receptor protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: beta 2 Adrenergic Receptor antibody [C2C3], C-term (GRP544) dilution: 1:250.
Various whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with beta 2 Adrenergic Receptor antibody [C2C3], C-term (GRP544) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary
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