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beta 2 Adrenergic Receptor antibody [C2C3], C-term
Catalog Number: GRP92
Product Overview
| Product Name | beta 2 Adrenergic Receptor antibody [C2C3], C-term |
|---|---|
| Catalog Number | GRP92 |
| Species/Host | Rabbit |
| Reactivity | Human, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P, WB |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human beta 2 Adrenergic Receptor. The exact sequence is proprietary. |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Liquid: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
|---|---|
| Concentration | 1 mg/ml |
| Storage | Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Purity | Purified by antigen-affinity chromatography. |
| Uniprot ID | P07550 |
| Entrez | 154 |
Product Description
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq]
Application Notes
| Dilution Range | WB: 1:500-1:3000,IHC-P: 1:100-1:1000 |
|---|
Validation Images
Sample (30 μg of whole cell lysate) A: PC-12 10% SDS PAGE GRP544 diluted at 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
beta 2 Adrenergic Receptor antibody [C2C3], C-term detects beta 2 Adrenergic Receptor protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: beta 2 Adrenergic Receptor antibody [C2C3], C-term (GRP544) dilution: 1:250.
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