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Product Overview
        
                           
                                                
                                                        
                                    
    
        | Product Name | Bax Polyclonal Antibody | 
|---|---|
| Catalog Number | GRP203 | 
| Species/Host | Rabbit | 
| Reactivity | Human, Mouse, Rat, Pig, Rabbit | 
| Conjugation | Unconjugated | 
| Tested applications | FC, ICC, IF, IHC-P, WB | 
| Immunogen | KLH conjugated synthetic peptide derived from human Bax (public_immunogen_range: 60-110/192) | 
| Alternative Names | (click to expand) | 
Product Properties
        
    
        Product Description
        
                           
                             
                    
    
        Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Application Notes
        
                           
                                                
                                                        
                                    
    
        
        | Dilution Range | WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200 | 
|---|
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