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BACE1 Polyclonal Antibody

Catalog Number: GRP208

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Datasheet
Product Overview
Product Name BACE1 Polyclonal Antibody
Catalog Number GRP208
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human BACE1 (public_immunogen_range: 451-501/501)
Alternative Names (click to expand) ASP2; BACE; HSPC104; Beta-secretase 1; Aspartyl protease 2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2; BACE1; KIAA1149
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID P56817
Entrez 23621
Product Description

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400
Validation Images
WB of GRP208
WB of GRP208
IHC-P of GRP208
IHC-P of GRP208
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