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ATG16L Polyclonal Antibody

Catalog Number: GRP534

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Datasheet
Product Overview
Product Name ATG16L Polyclonal Antibody
Catalog Number GRP534
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human ATG16A (public_immunogen_range: 530-580/607)
Alternative Names (click to expand) IBD10; WDR30; APG16L; ATG16A; ATG16L; Autophagy-related protein 16-1; APG16-like 1; ATG16L1; UNQ9393/PRO34307
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID Q676U5
Entrez 55054
Product Description

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Application Notes
Dilution Range WB: 1:300-1000, IHC-P: 1:200-400
Validation Images
WB of GRP534
WB of GRP534
IHC-P of GRP534
IHC-P of GRP534
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