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Product Overview
| Product Name | Anti-Hu LAR APC |
|---|---|
| Catalog Number | GRP13254 |
| Reactivity | Human, Primate |
| Tested applications | FC |
| Immunogen | WERI-RB-1 retinoblastoma cells |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | APC |
|---|---|
| Concentration | 0.1 mg/ml |
| Preservatives | Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
| Storage | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label. |
| Note | For research use only. |
| Isotype | Mouse IgG1 |
| Clone ID | W7C6 |
| Uniprot ID | G1UI20 |
| NCBI | 5792 |
Product Description
LAR is a receptore-linked transmembrane protein tyrosine phosphatase expressed on mesenchymal stem cells, that reside e.g. in bone marrow, blood, placenta, adipose tissue, or skin, as well as it is expressed on some carcinoma cell lines, including HeLa, MCF-7, or HT29. During the process of externalization, LAR is intracellularly proteolytically processed into two non-covalently associated subunits. This protein is involved in intercellular and cell-matrix interactions and its extracellular part resembles that of cell adhesion molecules (CAMs). The extracellular part can be released from the surface, which may be used for regulation of LAR function.
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