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Product Overview
| Product Name | Anti-Hu CD77 Purified |
|---|---|
| Catalog Number | GRP13263 |
| Reactivity | Human |
| Tested applications | FC, ICC, IHC-Fr |
| Immunogen | Daudi cell line (Burkitt´s lymphoma) |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Purified |
|---|---|
| Concentration | 1 mg/ml |
| Preservatives | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Note | For research use only. |
| Isotype | Lewis Rat IgM |
| Clone ID | 38.13 |
Product Description
CD77 (globotriaosylceramide Gb3), also known as the Pk blood group antigen, BLA (Burkitt´s lymphoma associated antigen), or CTH (ceramide trihexoside) is a neutral glycosphingolipid composed of three carbohydrate molecules linked to a lipid moiety in the cell membrane (Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer). It is expressed on germinal center B cells, Burkitt´s lymphoma cells, it can be induced on extrafolicular B cells and it is also found on endothelia and epithelia. CD77 may be involved in elimination of germinal center B cells that fail to produce high affinity antibodies, and serves also as receptor for shiga toxin and verotoxin.
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