Availability
- Request Lead Time
- In stock and ready for quick dispatch
Product Overview
Product Name | Anti-Hu CD41/CD61 (PAC-1 epitope) PE |
---|---|
Catalog Number | GRP13266 |
Reactivity | Human |
Tested applications | FC |
Immunogen | Human platelets |
Alternative Names | (click to expand) |
Product Properties
Form/Appearance | PE |
---|---|
Preservatives | Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
Storage | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label. |
Note | For research use only. |
Isotype | Mouse IgM kappa |
Clone ID | PAC-1 |
Product Description
CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation.
Reviews
Write Your Own Review