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Product Overview
        
                           
                                                
                                                        
                                    
    
        | Product Name | Anti-Hu CD170 Purified | 
|---|---|
| Catalog Number | GRP11557 | 
| Reactivity | Human, Primate | 
| Tested applications | ELISA, FC, ICC, IHC-Fr, IP | 
| Immunogen | Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1 | 
| Alternative Names | (click to expand) | 
Product Properties
        
                           
                                                
                                                        
                                    
    
        | Concentration | 1 mg/ml | 
|---|---|
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. | 
| Note | For research use only. | 
| Isotype | Mouse IgG1 | 
| Clonality | Monoclonal | 
| Clone ID | 1A5 | 
| Uniprot ID | O15389 | 
| NCBI | 8778 | 
Product Description
        
                           
                             
                    
    
        The mouse monoclonal antibody 1A5 recognizes an extracellular epitope of CD170 (Siglec-5, sialic acid binding Ig-like lectin 5), a transmembrane glycoprotein expressed strongly by neutrophils, macrophages activated during infections, monocytes, and dendritic cells. As in case with other anti-CD170 antibodies, this antibody crossreacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.
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