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Product Overview
| Product Name | Anti-Hu C5aR2 Purified |
|---|---|
| Catalog Number | GRP13275 |
| Reactivity | Human, Primate |
| Tested applications | FC, WB |
| Immunogen | L1.2 cells transfected with human C5aR2 |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Purified |
|---|---|
| Concentration | 1 mg/ml |
| Preservatives | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Note | For research use only. |
| Isotype | Mouse IgG2a kappa |
| Clone ID | 1D9-M12 |
| Uniprot ID | Q9P296 |
| NCBI | 27202 |
Product Description
C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.
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