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Product Overview
| Product Name | Anti-HDAC6 Purified |
|---|---|
| Catalog Number | GRP13255 |
| Reactivity | Human |
| Tested applications | ELISA, FC, ICC, WB |
| Immunogen | human HDAC6 |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Purified |
|---|---|
| Concentration | 1 mg/ml |
| Preservatives | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Note | For research use only. |
| Isotype | Mouse IgG1 kappa |
| Clone ID | 159 |
| Uniprot ID | Q9NSW6 |
| NCBI | 10013 |
Product Description
Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.
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