Availability

Anti-CD3 epsilon (activation epitope) FITC

Catalog Number: GRP11279

Product Overview
Product Name Anti-CD3 epsilon (activation epitope) FITC
Catalog Number GRP11279
Reactivity Human, Mouse
Tested applications FC
Immunogen Purified human CD3 proteins isolated from thymus
Alternative Names
Product Properties
Concentration 0.1 mg/ml
Storage Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Note For research use only.
Isotype Mouse IgG1
Clonality Monoclonal
Clone ID APA1/1
Uniprot ID P07766
NCBI 916
Product Description

The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

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