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Anti-CD3 epsilon (activation epitope) APC
Catalog Number: GRP11278
Product Overview
| Product Name | Anti-CD3 epsilon (activation epitope) APC |
|---|---|
| Catalog Number | GRP11278 |
| Reactivity | Human, Mouse |
| Tested applications | FC |
| Immunogen | Purified human CD3 proteins isolated from thymus |
| Alternative Names | (click to expand) |
Product Properties
| Concentration | 0.1 mg/ml |
|---|---|
| Storage | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label. |
| Note | For research use only. |
| Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Clone ID | APA1/1 |
| Uniprot ID | P07766 |
| NCBI | 916 |
Product Description
The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
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