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Product Overview
| Product Name | AMBP - Bikunin (50 µl) |
|---|---|
| Catalog Number | GRP12212 |
| Species/Host | Rabbit |
| Reactivity | Human |
| Predicted Reactivity | Bovine, Pig, Primates |
| Tested applications | ELISA, WB |
| Immunogen | human recombinant bikunin, UniProt: P02760, cleavage product no. PRO_0000017887 |
Product Properties
| Form/Appearance | Lyophilized |
|---|---|
| Storage | Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. |
| Note | For research use only. |
| Clonality | Polyclonal |
| Purity | Serum |
| MW | free bikunin 60-80 kDa |
| Uniprot ID | P02760 |
Application Notes
| Dilution Range | 1 : 2000 (ELISA), 1 : 2000 (WB) |
|---|---|
| Application Notes | Additional Information: This antibody is also reacting with the AMBP precursor. Background: Bikunin is a Kunitz-type protease inhibitor synthesized in the liver. The AMBP gene resides in the lipocalin cluster and encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Bikunin is found in blood and tissues both in free form and associated with heavy chains forming the inter-alpha-inhibitor family of proteins. Bikunin is a protease inhibitor, a component of extracellular matrix and exhibits anti-inflammatory activity in protection against cancer and inflammation. Reconstitution: For reconstitution add 50 µl of sterile water. |
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